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While glutathione is generally safe, some individuals may experience side effects such as allergic reactions, abdominal pain, and bloating

The enzyme inhibition might be due to alterations produced by ROS, which are triggered by GSH depletion caused by its consumption in the redox cycle of the quinone[50]

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Most genes, including Casp1 and Ptgs2os2 (a positive regulator of Cox-2 expression in cis and pro-inflammatory response regulator in trans ), showed a negative correlation between relative gene expression and the level of DNA methylation at that genes promoter site (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Marn L., Migulez E.M., Villar C.J., Lomb F